GENOME-WIDE ANALYSIS OF 53,400 PEOPLE WITH IRRITABLE BOWEL SYNDROME HIGHLIGHTS SHARED PATHWAYS WITH NEUROAFFECTIVE TRAITS

Chris Eijsbouts  ¹     Tenghao Zheng  ²     Nicholas A Kennedy  ³     Ferdinando Bonfiglio  ³     Carl Anderson  ⁴     Joanne Holliday  ⁵     Jing Shi  ⁶     Suyash Shringarpure  ⁶     Alexandru-Ioan Voda  ⁷     Gianrico Farrugia  ⁸     Andre Franke  ⁹     Matthias Hübenthal  ⁹     Goncalo Abecasis  ¹⁰     Matthew Zawistowski  ¹⁰     Anne Heidi Skogholt  ¹¹     Kristian Hveem  ¹¹     Tonu Esko  ¹²     Maris Teder-Laving  ¹²     Alexandra Petrovna Zhernakova  ¹³     Michael Camilleri  ¹⁴     Guy E. Boeckxstaens  ¹⁵     Peter Whorwell  ¹⁶     Robin Spiller  ¹⁷     Gil McVean  ¹⁷     Mauro D'Amato  ¹⁸     Luke Jostins  ¹⁸     Miles Parkes  ^19    
1 Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, United Kingdom
² Center for Molecular Medicine & Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden
³ IBD Pharmacogenetics, College of Medicine and Health, University of Exeter, Exeter, United Kingdom
⁴ Wellcome Sanger Institute, Hinxton, United Kingdom
⁵ University of Oxford, Oxford, United Kingdom
⁶ 23andMe, Inc., Sunnyvale, United States
⁷ Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom
⁸ Mayo Clinic Gastroenterology and Hepatology, Rochester, United States
⁹ Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany
¹⁰ University of Michigan, School of Public Health, Ann Arbor, United States
¹¹ Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway
¹² Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
¹³ University Medical Center Groningen, Groningen, Netherlands
¹⁴ Clinical Enteric Neuroscience Translational and Epidemiological Research and Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, United States
¹⁵ Translational Research Center for Gastrointestinal Disorders, KU Leiven, Leuven, Belgium
¹⁶ Neurogastroenterology Unit, Wythenshawe Hospital, Centre for Gastrointestinal Sciences, University of Manchester, Manchester, United Kingdom
¹⁷ Nottingham Digestive Diseases Centre, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom
¹⁸ School of Biological Sciences, Monash University, Clayton VIC, Australia
¹⁹ Division of Gastroenterology and Hepatology, University of Cambridge, Cambridge, United Kingdom

Session
IBS II

Conference
UEG Week Virtual 2020

Citation
United European Gastroenterology Journal 2020; 8 (Supplement 1)