Research Projects

Project HoloSurge

Multimodal 3D Holographic tool and real-time Guidance System with point-of-care diagnostics for surgical planning and interventions on liver and pancreatic cancers 

Programme and Topic: HORIZON.2.1.5 - Tools, Technologies and Digital Solutions for Health and Care, including personalised medicine 

Project duration: 2024 – 2027  

UEG takes an active part in the project HoloSurge as a dissemination partner.

HoloSurge logo

HoloSurge is a joint undertaking that brings European scientists and clinicians from high-tech companies, clinical centres, and research institutions in a consortium to deploy an innovative AI-based medical system that

  • enables automatic fusion and segmentation of state-of-the-art imaging modalities for interactive 3D holographic visualization of patients’ organs;
  • provides real-time surgical navigation, and
  • allows real-time cell-level cancer diagnostics. 

The solution will provide surgical teams with an unmatched holistic view of the patient’s anatomy and pathology in real-time at the point of care, before and during surgery. This innovation will be validated for cancer interventions while creating a trail of better-informed perioperative decision-making that can save countless lives. 

This project has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No Project 101137233 — HoloSurge. Horizon Europe is the EU’s key funding programme for research and innovation, with a budget of €95.5 billion. 

Read press release Access official factsheet Visit HoloSurge website 

Co-funded by the EU

Co-funded by the European Union. Views and opinions expressed are, however, those of the author(s) only and do not necessarily reflect those of the European Union or the European Health and Digital Executive Agency (HADEA). Neither the European Union nor the granting authority can be held responsible for them.


Project INTERCEPT – Pioneering a future without Crohn’s Disease

Full name: Verification and validation of a biomarker panel that identifies individuals at high risk to develop Crohn’s Disease allowing INTERCEPTION of full-blown disease development. 

Programme and Topic: Clinical validation of biomarkers for diagnosis, monitoring disease progression and treatment response HORIZON-JU-IHI-2024-07-03 

Project duration: 2025 – 2029 

UEG supports this pioneering European study as an official dissemination partner.  

Intercept

The INTERCEPT project aims to verify and clinically validate a panel of biomarkers and build a blood risk score that can identify individuals with a high risk of developing Crohn’s Disease within five years after initial evaluation. The project will recruit 10,000 healthy first-degree relatives of individuals with Crohn’s Disease from seven European countries to further validate the biomarkers and risk score. From this group, 80 with the highest risk of developing Crohn’s Disease will take part in an innovative trial aimed at preventing full-blown disease development through an established and highly effective medical treatment.

This early detection and prevention method has the potential to revolutionise the way we understand and treat Crohn’s Disease. It would enable healthcare professionals to diagnose the disease early on, potentially keeping it from progressing to debilitating stages. INTERCEPT is setting its sights on a future where Crohn’s Disease is highly manageable or even avoidable; committing itself to improving the lives of patients and their families.

Read press release Visit INTERCEPT  

The project INTERCEPT is supported by the Innovative Health Initiative Joint Undertaking (IHI JU) under grant agreement No 101194766. The JU receives support from the European Union’s Horizon Europe Research and Innovation Programme and COCIR, EFPIA, Europa Bío, MedTech Europe, Vaccines Europe, MoonLake Immunotherapeutics AG, ROPCA ApS, Scienta Lab, and Collective Minds Radiology AB. 

Co-Funded by the European Union, the private members, and those contributing partners of the IHI JU. Views and opinions expressed are, however, those of the author(s) only and do not necessarily reflect those of the aforementioned parties. Neither of the aforementioned parties can be held responsible for them. 

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Project InfoGut COST Action 

Full Name: CA23110 - International networking on in vitro colon models simulating gut microbiota mediated interactions (INFOGUT)
 
Programme and Topic: COST ACTION 2023, COST – European Cooperation in Science and Technology is a funding organisation for research and innovation networks

Project duration: October 9, 2024 – October 8, 2028

UEG supports the InfoGut COST Action by contributing to its communication and dissemination activities.
The InfoGut COST Action aims to fill the knowledge gap on in vitro colon models by developing consensus protocols and robust data sets. These will advance our understanding of the events taking place in the intestinal milieu, including the complex interactions between the microbiota and the host.

Apply to join the working groups that match your interests!

Visit official InfoGut website

InfoGut on the COST Actions website

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Project PALACROS

Full name: Prioritising multimodal surgical care for patients with locally advanced pancreatic cancer across Europe 

Programme and Topic: HORIZON-MISS-2025-02-CANCER-03 – Innovative surgery as the cornerstone of affordable multi-modal therapeutic interventions benefitting cancer patients with locally advanced or metastatic disease

Project duration: 2026 – 2032 

UEG supports the PALACROS consortium by contributing to dissemination and stakeholder outreach, helping to communicate project outcomes to the European digestive health community. 

PALACROS is an EU-funded Horizon Europe Research and Innovation Action dedicated to improving multimodal, surgery-centred care for patients with locally advanced pancreatic cancer across Europe. Coordinated by Amsterdam UMC, the project brings together clinical and academic centres, patient organisations and innovative partners to strengthen evidence-based treatment strategies and improve access to specialised care. 

The project will combine randomised clinical trials, a European training programme and AI-supported radiology tools to improve patient selection, support multidisciplinary decision-making and help reduce inequalities in access to high-quality pancreatic cancer care. PALACROS also places strong emphasis on patient involvement, including patient-centred outcomes such as quality of life, decision-making, symptoms, emotional well-being and daily functioning. 

Through its integrated approach, PALACROS aims to provide the clinical evidence, training structures, digital tools and implementation roadmap needed to improve outcomes for patients with locally advanced pancreatic cancer and support more equitable cancer care across Europe.

Read press release

Access official factsheet

This project has received funding from the European Union’s Horizon Europe research and innovation programme under Grant Agreement No. 101288659. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Health and Digital Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.