NOVEL PLATINUM-BASED CHEMOTHERAPEUTIC AGENTS HALT CHOLANGIOCARCINOMA PROGRESSION THROUGH THE INDUCTION OF DOUBLE-STRAND DNA BREAKS, PREVENTING DNA REPAIR MECHANISMS

Irene Olaizola  ¹     Mikel Odriozola  ²     Maitane Asensio  ^{3, 4}     Paula Olaizola  ^{5, 6}     Ivan Rivilla  ^{2, 7}     Amanda Guimaraes  ⁷     Francisco Javier Caballero Camino  ⁷     Elisa Herráez  ^{3, 4}     Oscar Briz  ^{3, 4}     Pedro M. Rodrigues  ^{5, 6}     María Jesús Perugorria  ^{5, 6}     Luis Bujanda Fernández de Piérola  ^{5, 6}     Jose J. Garcia-Marin  ^{3, 4}     Fernando Cossio  ⁴     Jesús M. Bañales  ^{5, 6    
1} Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain
² Center of Innovation in Advanced Chemistry (ORFEO-CINQA), Faculty of Chemistry, University of the Basque Country (UPV/EHU) and Donostia International Physics Center (DIPC), San Sebastian, Spain
³ Experimental Hepatology and Drug Targeting (HEVEPHARM) Group, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain
⁴ National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Insti
⁵ Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain
⁶ National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos I
⁷ IKERBASQUE, Basque Foundation for Science, Bilbao, Spa

Topic
Hepatobiliary

Session
PP 07 Liver & biliary (Posters)

Conference
UEG Week 2023

Citation
United European Gastroenterology Journal 2023; 11 (Supplement 8)