GUSELKUMAB, AN IL-23P19 SUBUNIT–SPECIFIC MONOCLONAL ANTIBODY, BINDS CD64 ON THE SURFACE OF IL-23-SECRETING MYELOID CELLS, CAPTURES LOCALLY PRODUCED IL-23, AND DELIVERS IL-23 TO INTRACELLULAR COMPARTMENTS

Raja Atreya  1     Maria T. Abreu  2     James G. Krueger  3     Kilian Eyerich  4, 5     Robert Bissonnette  6     Carrie Greving  7     Brian Stoveken  8     Deeper Hammaker  8     Kristen Leppard  8     John Hartman  8     Indra Sarabia  8     Matthew Duprie  8     Joseph Brown  8     M. Merle Elloso  9     Phuc Bao  9     Eilyn Lacy  9     Kacey Sachen  9     Christopher Ritchlin  10     Iain B. McInnes  11     Matthieu Allez  12     Anne Fourie  12    
1 Erlangen University Hospital, Erlangen, Germany
2 University of Miami, Miami, FL, United States
3 The Rockefeller University, New York, NY, United States
4 Medical Center, Freiburg, Germany
5 Karolinska Institute, Stockholm, Sweden
6 Innovaderm Research Inc., Montréal, Québec, Canada
7 Janssen Research & Development, LLC, San Diego, CA, United States
8 Janssen Research & Development, LLC, Spring House, PA, United States
9 Janssen Scientific Affairs, LLC, Horsham, PA, United States
10 University of Rochester, Rochester, NY, United States
11 University of Glasgow, Glasgow, United Kingdom
12 Hôpital Saint-Louis, Université Paris Cité, Paris, France

Topic
IBD

Conference
UEG Week 2023

Citation
United European Gastroenterology Journal 2023; 11 (Supplement 8)


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