Author

Hiromichi Shimizu 1

1 Tokyo Medical and Dental University,Tokyo

5-aminosalicylate intolerance is associated with a poor prognosis in patients with Ulcerative colitis

Toshimitsu Fujii, Shuji Hibiya, Eiko Saito, Kento Takenaka, Kohei Suzuki, Maiko Motobayashi, Hiromichi Shimizu, Masakazu Nagahori, Kazuo Ohtsuka, Tsunehito Yauchi, Masayuki Kurosaki, Mamoru Watanabe

COMPLETE CONVERSION OF CRYPT PROGENITOR CELLS INTO ATOH1-POSITIVE CELLS BY TARGETED DELETION OF DLL1 AND DLL4 IN LGR5-POSITIVE INTESTINAL STEM CELLS.

Hiromichi Shimizu, Ryuichi Okamoto, Toru Nakata, Satoru Fujii, Go Ito, Tatsuro Murano, Kiichiro Tsuchiya, Mamoru Watanabe

ECTOPIC EXPRESSION OF REG3A IN THE MICE DISTAL COLON IS MEDIATED BY INTERACTIONS BETWEEN NOTCH AND IL-22 SIGNALING PATHWAYS, AND PROMOTES TISSUE REPAIR BY THE AUGMENTATION OF EGFR SIGNALING

Fumiaki Ishibashi, Konomi Kuwabara, Ami Kawamoto, Sho Anzai, Junichi Takahashi, Sayaka Nagata, Hiromichi Shimizu, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, Ryuichi Okamoto

IL-22-MEDIATED ANTIMICROBIAL RESPONSE IS REGULATED BY HES1 VIA STAT3-DEPENDENT TRANSCRIPTION IN HUMAN INTESTINAL EPITHELIAL CELLS

Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Satoru Fujii, Toru Nakata, Kiichiro Tsuchiya, Mamoru Watanabe

LINEAGE-SPECIFIC EXPRESSION OF BESTROPHIN-2 AND BESTROPHIN-4 IS REGULATED BY NOTCH SIGNALING IN HUMAN INTESTINAL EPITHELIAL CELLS.

Go Ito, Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kiichiro Tsuchiya, Mamoru Watanabe

LONG-LIVED SECRETORY CELLS RESIDING IN THE MOUSE PROXIMAL COLON SERVE AS RESERVE STEM CELLS UNDER DNA DAMAGE-INDUCED MUCOSAL INJURY

Konomi Kuwabara, Fumiaki Ishibashi, Ami Kawamoto, Sho Anzai, Junichi Takahashi, Sayaka Nagata, Hiromichi Shimizu, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, Ryuichi Okamoto

NOTCH SIGNALING AND TNF-Α SYNERGISTICALLY PROMOTES INTRACELLULAR PROTEIN ACCUMULATION OF OLFM4 IN THE INFLAMED MUCOSA OF ULCERATIVE COLITIS

Go Ito, Ryuichi Okamoto, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Kiichiro Tsuchiya, Mamoru Watanabe

NOTCH SIGNALING REGULATES EXPRESSION OF GELSOLIN SUPERFAMILY GENES, GELSOLIN AND SCINDERIN, AND PROMOTES RE-ASSEMBLY OF ACTIN CYTOSKELTON IN HUMAN INTESTINAL EPITHELIAL CELLS

Ryuichi Okamoto, Go Ito, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Mamoru Watanabe

REPROGRAMMED ATOH1+ INTESTINAL EPITHELIAL CELLS CONTRIBUTE TO REGENERATE DAMAGED COLONIC MUCOSA IN DSS-INDUCED COLITIS

Fumiaki Ishibashi, Hiromichi Shimizu, Ami Kawamoto, Go Ito, Toru Nakata, Satoru Fujii, Kohei Suzuki, Reiko Kuno, Sho Anzai, Konomi Kuwabara, Mao Kawai, Junichi Takahashi, Minami Hama, Sayaka Nagata, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Mamoru Watanabe

THE UBIQUITIN-LIKE PROTEIN UBIQUITIN D IS UP-REGULATED BY SYNERGY OF NOTCH AND PRO-INFLAMMATORY CYTOKINES IN THE INFLAMED INTESTINAL EPITHELIA OF IBD PATIENTS.

Ami Kawamoto, Go Ito, Toru Nakata, Satoru Fujii, Kohei Suzuki, Fumiaki Ishibashi, Hiromichi Shimizu, Sayaka Nagata, Sho Anzai, Reiko Kuno, Konomi Kuwabara, Mao Kawai, Junichi Takahashi, Minami Hama, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Mamoru Watanabe

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