European Guideline on Achalasia – UEG and ESNM recommendations

Neurogastroenterology & Motility, Oesophagus

United European Gastroenterology Journal 2020, Vol. 8(1) 13–34


This guideline was developed with the support of a UEG Activity Grant.


Achalasia is a primary motor disorder of the oesophagus characterised by absence of peristalsis and insufficient lower oesophageal sphincter relaxation. With new advances and developments in achalasia management, there is an increasing demand for comprehensive evidence-based guidelines to assist clinicians in achalasia patient care.

These guidelines were established in accordance with the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument. A systematic review of the literature was performed and the certainty in the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. Recommendations were voted upon using a nominal group technique.

These guidelines specifically focus on the definition of achalasia, treatment aims, diagnostic tests, medical, endoscopic and surgical therapy, management of treatment failure, follow-up and oesophageal cancer risk.

These multidisciplinary UEG and ESNM guidelines provide a comprehensive evidence-based framework with recommendations on the diagnosis, treatment and follow-up of adult achalasia patients.

Keywords: Dysphagia; oesophagus; manometry; myotomy; motility; esophagus

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Source File

Publishing organization(s):

ESNM European Society of Neurogastroenterology and Motility, UEG (United European Gastroenterology)

Scientific area:

Neurogastroenterology & Motility, Oesophagus

Year of publication:

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