Author

Stuart M. Brierley 1

1 University of Adelaide

ACTIVATION OF THE GUANYLATE CYCLASE-C/CGMP PATHWAY DECREASES GASTROINTESTINAL PAIN

Immaculada Silos-Santiago, Hong Jin, Marco Kessler, Mark G. Currie, Gerhard Hannig, Ashley Blackshaw, Caroline B. Kurtz, Mark G. Currie, Stuart M. Brierley

CHRONIC ORAL ADMINISTRATION OF THE GUANYLATE CYCLASE-C AGONIST LINACLOTIDE ATTENUATES COLITIS INDUCED LONG-TERM BLADDER AFFERENT HYPERACTIVITY

Luke Grundy, Sonia Garcia-Caraballo, Jessica Maddern, Grigori Rychkov, Gerhard Hannig, Caroline B. Kurtz, Immaculada Silos-Santiago, Stuart M. Brierley

DIFFERENT SUBTYPES OF PATIENTS WITH IRRITABLE BOWEL SYNDROME HAVE DISTINCT ALTERATIONS IN THE GUANYLATE CYCLASE-C/CYCLIC GMP PATHWAY

Andrea M. Harrington, Richard L. Young, Caroline B. Kurtz, Immaculada Silos-Santiago, Quoc Nam Nguyen, Jane Andrews, Stuart M. Brierley

DIFFERENTIAL EFFECTS OF EXTRACELLULAR CYCLIC GMP (CGMP) AND THE GUANYLATE CYCLASE-C (GC-C) AGONIST, LINACLOTIDE, ON MOUSE GASTRIC VAGAL AFFERENT MECHANOSENSITIVITY

Stephen Kentish, Tracey O'Donnell, Stuart M. Brierley, Caroline B. Kurtz, Amanda Page

EXPRESSION AND LOCALIZATION OF CANNABINOID RECEPTORS AND THE EFFECT OF OLORINAB, A PERIPHERALLY ACTING, HIGHLY SELECTIVE, FULL AGONIST OF THE CANNABINOID RECEPTOR 2, ON VISCERAL HYPERSENSITIVITY IN RODENT MODELS OF IRRITABLE BOWEL SYNDROME AND INFLAMMATORY BOWEL DISEASE

Joel Castro, Sonia Garcia-Caraballo, Jessica Maddern, Gudrun Schober, Beatriz Lindstrom, Shirdi Schmiel, Stuart M. Brierley

EXTRACELLULAR CYCLIC GMP, THE DOWNSTREAM MEDIATOR RELEASED IN RESPONSE TO LINACLOTIDE-INDUCED ACTIVATION OF GUANYLATE CYCLASE C, REDUCES EXCITABILITY OF MURINE AND HUMAN DORSAL ROOT GANGLION NEURONS

Andrea Ghetti, Andrea M. Harrington, Caroline B. Kurtz, Immaculada Silos-Santiago, Stuart M. Brierley

GUANYLATE CYCLASE-C EXPRESSION IS DOWN-REGULATED IN COLONIC BIOPSIES FROM FEMALE IRRITABLE BOWEL SYNDROME PATIENTS WITH CONSTIPATION

Sonia Garcia-Caraballo, Andrea M. Harrington, Joel Castro, Gerhard Hannig, Caroline B. Kurtz, Immaculada Silos-Santiago, Lin Chang, Stuart M. Brierley

LINACLOTIDE-INDUCED CHRONIC ACTIVATION OF THE GUANYLATE CYCLASE-C/CYCLIC GMP PATHWAY INHIBITS ASCENDING NOCICEPTIVE PATHWAYS AND RESTORES ABERRANT SPINAL CORD SIGNALLING

Joel Castro, Andrea M. Harrington, Sonia Garcia-Caraballo, Jessica Maddern, Tracey O’Donnell, Luke Grundy, Caroline B. Kurtz, Immaculada Silos-Santiago, Stuart M. Brierley

MODULATION OF MUCOSAL SENSITIVITY VIA THE EPITHELIAL GUANYLATE CYCLASE-C/CYCLIC GMP PATHWAY: LINACLOTIDE AS A REGULATOR OF VISCERAL SENSATION

Andrea M. Harrington, Joel Castro, Sonia Garcia-Caraballo, Jessica Maddern, Tracey O’Donnell, Luke Grundy, Grigori Rychkov, Caroline B. Kurtz, Immaculada Silos-Santiago, Stuart M. Brierley

Preclinical and Clinical Efficacy of Olorinab, a Peripherally Restricted, Highly Selective Full Agonist of the Cannabinoid Type 2 Receptor for the Management of Visceral Pain in Inflammatory Bowel Disease

Bruce Yacyshyn, Stuart M. Brierley, Beatriz Lindstrom, John Adams, Stewart Turner, Brett A. English, Kathe Stauber, Peter D.R. Higgins

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