Author

Pierre-Olivier Frappart 1

1 Ulm University,Ulm,Germany

A COHERENT ROADMAP TO GENERATE EITHER PANCREATIC ACINAR OR DUCT-LIKE CELLS FROM HUMAN PLURIPOTENT STEM CELLS CHALLENGES PANCREATIC CANCER BIOLOGY

Jessica Merkle, Markus Breunig, Meike Hohwieler, Sandra Heller, Thomas Seufferlein, Pierre-Olivier Frappart, Alexander Kleger

A NOVEL SYNERGISTIC THERAPY APPROACH TO TREAT DNA DAMAGE REPAIR DEFICIENT PANCREATIC CANCER

Johann Gout, Lukas Perkhofer, Mareen Morawe, Frank Arnold, Michaela Ihle, Stephanie Biber, Elodie Roger, Johann M Kraus, Katja Stifter, Hans A Kestler, Thomas Seufferlein, Lisa Wiesmüller, Pierre-Olivier Frappart, Alexander Kleger

ACTIONABLE PERTURBATIONS IN THE DNA DAMAGE RESPONSE ESTABLISH SYNERGISTIC THERAPEUTIC ROUTES IN ATM DEFICIENT PANCREATIC CANCER

Lukas Perkhofer, Johann Gout, Frank Arnold, Pierre-Olivier Frappart, Alexander Kleger

ATM-DEFICIENCY GENERATES GENOMIC INSTABILITY IN PANCREATIC DUCTAL ADENOCARCINOMA AND SENSITIZES TOWARD THERAPEUTIC DNA-DAMAGE

Lukas Perkhofer, Anna Schmitt, Elisabeth Hessmann, Dietrich Alexander Alexander Ruess, Marina Lesina, Albrecht Neese, Bence Sipos, Thomas Seufferlein, Hans Christian Reinhardt, Pierre-Olivier Frappart, Alexander Kleger

FUNCTIONAL GENOMIC SCREENING DURING SOMATIC CELL REPROGRAMMING IDENTIFIES DKK3 AS A ROADBLOCK OF PANCREATIC REGENERATION

Johann Gout, Markus Breunig, Lukas Perkhofer, Thomas Seufferlein, Pierre-Olivier Frappart, Alexander Kleger

PARP INHIBITOR RESISTANCE INDUCES MASSIVE GENOME ALTERATIONS RESPONSIBLE OF THE ACQUISITION OF MULTIDRUG RESISTANCE IN DNA DAMAGE REPAIR-DEFICIENT PANCREATIC CANCER

Johann Gout, Lukas Perkhofer, Mareen Morawe, Frank Arnold, Elodie Roger, Martin Müller, Thomas Seufferlein, Pierre-Olivier Frappart, Alexander Kleger

RINT1 IS ESSENTIAL TO PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) HOMEOSTASIS

Frank Arnold, Ewa K Kaminska, Johann Gout, Lukas Perkhofer, Pierre-Olivier Frappart, Alexander Kleger

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