Author

André Lopes Simão 1

1 iMed.ULisboa, Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal

ACTIVATION OF NECROPTOSIS IN HUMAN AND EXPERIMENTAL CHOLESTASIS

Marta Bento Afonso, Pedro M. Rodrigues, André Lopes Simão, Helena Cortez-Pinto, Dimitry Ofengeim, Joana D. Amaral, Rui Eduardo Castro, Junying Yuan, Cecília Maria Pereira Rodrigues

DEOXYCHOLIC ACID INDUCES MIR-21/PDCD4-DEPENDENT CYTOTOXICITY BY HAMPERING NF-ΚB SURVIVAL SIGNALLING IN PRIMARY RAT HEPATOCYTES

Pedro Miguel Rodrigues, André Lopes Simão, Cecília Maria Pereira Rodrigues, Rui Eduardo Castro

DEOXYCHOLIC ACID INHIBITS NF-ΚB-MEDIATED ACTIVATION OF MIR-21 IN PRIMARY RAT HEPATOCYTES, PROMOTING APOPTOSIS IN A DOSE-DEPENDENT MANNER

Pedro Miguel Rodrigues, Marta Bento Afonso, André Lopes Simão, Pedro Miguel Borralho, Duarte Miguel Sacramento Ferreira, Pedro Miguel Borralho, Cecília Maria Pereira Rodrigues, Rui Eduardo Castro

DUAL TARGETING OF MICRORNA-21 AND FXR AMELIORATES NAFLD PATHOGENESIS IN MICE

Pedro Miguel Rodrigues, Marta Bento Afonso, André Lopes Simão, Marta Caridade, Catarina Cruz Carvalho, Alexandre Trindade, António Duarte, Pedro Miguel Borralho, Mariana V Machado, Helena Cortez-Pinto, Cecília Maria Pereira Rodrigues, Rui Eduardo Castro

EXTRACELLULAR VESICLES FROM TGR5-ACTIVATED ADIPOCYTES ELICIT ANTI-INFLAMMATORY EFFECTS UPON HEPATOCYTES EXPOSED TO NAFLD-ASSOCIATED PATHOGENIC STIMULI

André Lopes Simão, Daniela F. Silva, Margarida Cruz, Diogo A. E. Fernandes, Mariana M. Henrique, Carolina S. Palma, Bruno Costa-Silva, Cecília Maria Pereira Rodrigues, Maria L. Martinez-Chantar, Kristina Schoonjans, Jesús M. Bañales, Rui Castro

IMPROVING METABOLIC PARAMETERS IN NAFLD BY TARGETING NUCLEAR RECEPTORS

Pedro Miguel Rodrigues, Marta Bento Afonso, André Lopes Simão, Marta Caridade, Catarina C Carvalho, Alexandre Trindade, António Duarte, Pedro Miguel Borralho, Mariana Verdelho Machado, Helena Cortez-Pinto, Cecília Maria Pereira Rodrigues, Rui Eduardo Castro

Liver and skeletal muscle miR-34a contributes to mitochondrial dysfunction and insulin resistance in experimental NAFLD

André Lopes Simão

LIVER AND SKELETAL MUSCLE MIR-34A CONTRIBUTES TO MITOCHONDRIAL DYSFUNCTION AND INSULIN RESISTANCE IN EXPERIMENTAL NAFLD

André Lopes Simão, Marta Bento Afonso, Pedro M. Rodrigues, Cecília Maria Pereira Rodrigues, Rui Eduardo Castro

LIVER MICRORNA-34A IS ACTIVATED IN MULTIPLE ANIMAL MODELS OF NAFLD AND CORRELATES WITH KEY DISEASE HALLMARKS IN HUMAN PATIENTS

André Lopes Simão

Liver microRNA-34a is activated in multiple animal models of NAFLD and correlates with key disease hallmarks in human patients

André Lopes Simão, Pedro Miguel Rodrigues, Marta Bento Afonso, Alvaro Santos-Laso, Raul Jimenez-Agüero, Emma Eizaguirre, Luis Bujanda Fernández de Piérola, Maria J Pareja, Jesús M. Bañales, Cecília M. P. Rodrigues, Rui Eduardo Castro

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